Saltville, Va. Karen Marie Holmes, age 69, passed away Sunday, December 12, 2021, at Johnston Memorial Hospital in Abingdon, Va. She was preceded in death by her parents, Rev. C. C. Olinger and Wanda Minton Olinger; and brother, Clayborne Olinger. Karen is survived by her husband, Mark Holmes; brother, Alvin Olinger and wife Linda; brother-in-law, David Holmes and wife Donna; sister-in-law, Jody Olinger Orr; nieces and nephews, Stacy Niece, Sheena Henderson, Douglas Petrick, and David Petrick; great nieces and nephews, Lexie, Lacey, Brody, Joslyn, Axl, Riley, Madison, Carter, Krysta, and Bentley; special friend, Lisa Holmes and family. Funeral services will be held at 7:00 p.m. on Thursday, December 16, 2021, at Henderson Funeral Home with Victor Oberholtzer officiating. The family will receive friends from 6 until 7:00 p.m. prior to the service. A graveside service will be held at 11:30 a.m. on Friday, December 17, 2021, at Mount Rose Cemetery in Glade Spring, Va. Online condolences may be expressed at drhendersonfuneralhome.com. The D.R. Henderson Funeral Home is honored to be serving the Karen Marie Holmes family.